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Terminology Services


Integrated Risk Information System (IRIS) Glossary

Description: 
This glossary contains definitions of terms used frequently in IRIS Program assessments and related materials. These definitions assumed that the user has some familiarity with risk assessment and health science.
Publishing Organization: 
Office of Research and Development/Center for Public Health and Environmental Assessment/Chemical and Pollutant Assessment Division
Last Update: 
June 22, 2022
Program Site: 
 

Terms & Acronyms


Contains Begins Exact Match

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Term
Acceptable Daily Intake
Acute Exposure
Acute Reference Concentration
Acute Reference Dose
Acute Toxicity
Added Risk
Additional Risk
Adverse Effect
Aerodynamic Diameter
Aerosol
Anecdotal Data
Attributable Risk
Average Daily Dose
Background Levels
Benchmark Concentration
Benchmark Dose
Benchmark Response
Benign Tumor
Bioassay
Bioavailability
Biologically Based Dose Response Model
Blood to Air Partition Coefficient
BMCL
BMDL
Cancer
Carcinogen
Carcinogenesis
CAS Registry Number
Case-control Study
Chronic Effect
Chronic Exposure
Chronic Reference Concentration
Chronic Reference Dose
Chronic Study
Chronic Toxicity
Co-carcinogen
Cohort Study
Confounder
Confounding Factor
Control Group
Critical Concentration
Critical Effect
Critical Study
Developmental Toxicity
Dose
Dose-Response Assessment
Dose-Response Relationship
Effective Dose
Endpoint
Epidemiology
Estimated Exposure Dose
Excess Lifetime Risk
Exposure
Exposure Assessment
Extra Risk
Extrapolation, low dose
Forced Expiratory Volume
Forced Vital Capacity
Frank Effect Level
Functional Residual Capacity
Gamma (Multi-Hit) Model
Guidelines (human health risk assessment)
Hazard
Hazard Assessment
Hazard Characterization
Human Equivalent Concentration
Human Equivalent Dose
Incidence
Incidence Rate
Individual Risk
Inhalation Unit Risk
Initiation
Interspecies Dose Conversion
Latency Period
Limited Evidence
Linear Dose Response
Linearized Multistage Procedure
Logistic Model
Longer-Term Exposure
Lower Limit on Effective Dose ₁₀
Lowest-Observed-Adverse-Effect Level
Lowest-Observed-Effect Level
Malignant Tumor
Margin of Exposure
Mass Median Aerodynamic Diameter
Maximum Likelihood Estimate
Maximum Likelihood Method
Metastasis
Model
Modifying Factor
Monte Carlo Technique
Multistage Model
Multistage Weibull Model
Mutagen
Neoplasm
No-Observed-Adverse-Effect Level
No-Observed-Effect Level
Non-Linear Dose Response
Odds Ratio
Oncogenic
One Hit Model
Oral Slope Factor
Organoleptic
Pharmacodynamics
Pharmacokinetics
Physiologically Based Pharmacokinetic Model
Point of Departure
ppb
ppm
Prevalence
Principal Study
Probit Model
Promoter
Proportionate Mortality Ratio
Prospective Study
Reference Concentration
Reference Dose
Reference Group
Reference Value
Regional Deposited Dose
Regional Deposited Dose Ratio
Regional Gas Dose
Regional Gas Dose Ratio
Relative Risk
Reserve Volume
Residual Volume
Risk Assessment (human health)
Risk Characterization
Risk Difference
Risk (human health)
Risk Management (human health)
Risk Ratio
Short Term Exposure
Short Term Reference Concentration
Short Term Reference Dose
Sigma g
Slope Factor
Standardized Mortality Ratio
Statistical Significance
Subchronic Exposure
Subchronic Reference Concentration
Subchronic Reference Dose
Subchronic Study
Sufficient Evidence
Superfund
Supporting Studies
Susceptibility
Susceptible Subgroups
Systemic Effects
Systemic Toxicity
Target Organ
Teratogenic
Threshold
Threshold Limit Value
Tidal Volume
Total Lung Volume
Toxic Substance
Toxicity
Toxicodynamics
Toxicokinetics
Toxicology
Tumor
Tumor Progression
Uncertainty
Uncertainty Factor
Unit Risk
Upper Bound
Variability
Variability Factor
Vital Capacity
Weibull Model
Weight-of-Evidence for Carcinogenicity
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